Studies on an eosinophil differentiation factor produced by a T-hybrid line.

Studies on an eosinophil differentiation factor produced by a T-hybrid line by David John Warren Download PDF EPUB FB2

Apart from the factor-dependent eosinophil growth/differentiation described, the human promyelocytic leukemia cell line, HL cells, can also differentiate. Interleukin-5 (IL-5) is an eosinophil differentiation factor.

Therefore, increased levels of IL-5 in the bone marrow are associated with increased eosinophil numbers in blood. Distinct T cell subsets or their secreted products exert specific and/ or nonspecific regulatory signals of helper or suppressor nature. The low frequency of antigen-specific helper T cells and lack of methods for their enrichment and subsequent cultivation imposed difficulties in studies on T cell function and also hampered the chemical Author: Edna Mozes, Ron N.

Apte. Abstract. Regulation of immune responses by T lymphocytes is mediated mainly by the release of soluble factors, which can be either specific (Lonai et al., ; Sorensen et al., ) or nonspecific (Pick, ; Pierce and Kapp, ).Studies on the structure and function of these important mediators have been hampered by the great heterogeneity of crude preparations Author: Junming Le, Jan Vilček, Wolf Prensky.

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When using anti-immunoglobulin affinity columns to isolate a particularly valuable antibody, e.g. a monoclonal antibody produced by a hybridoma cell line, it is good practice to saturate high-affinity anti-immunoglobulin sites by a cycle of pretreatment with normal mouse immunoglobulin and acid elution.

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